The Bar Sinister: Does Handlebar Level Damage the Pelvic Floor in Female Cyclists?
-- Partin et. al., The Journal of Sexual Medicine, 5 MAR 2012

Handlebars positioned lower than the saddle were significantly associated with increased perineum saddle pressures and decreased genital sensation in female cyclists.

Note: Dr. Simon Bar Sinister was the main antagonist in the Underdog cartoon show.