Part of the human struggle is to understand the world around us, to understand ourselves, and to have some level of control of our lives by being able to predict at least the basic patterns and rhythms of the world. Ancient cultures made calendars and monuments to help them predict the seasons, for example. Accurate knowledge is difficult, however, especially since we live in a world that is far more complex than the one in which our poor monkey brains evolved.
One advantage of the skeptical world view is that it seeks to understand the weaknesses and biases of human cognition, and it respects accurate knowledge over our emotional desires and needs. Skeptics attempt to see the world as it actually is, not how they might want it to be. Examples of what can happen when you take an unskeptical view abound.
-- Steve Novella, Escape to New Age Mountain